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A study published in the Journal of the American Medical Association found that varenicline and nicotine replacement therapy (NRT) combined was more effective than varenicline alone. More than 400 adults were randomized to receive varenicline plus either a 15-mg nicotine patch or placebo patch. The combination therapy group achieved higher abstinence rates at 12 weeks (end of treatment) and at 6 months. Further studies are needed to assess long-term efficacy and safety. Read more about the study.

A recent issue of JAMA is focused on smoking and smoking cessation. It addresses several topics including a reflection on 50 years of tobacco control since the first U.S. Surgeon General’s report on smoking, e-cigarettes, quitting smoking unassisted, smoking cessation and mental illness, pharmacological treatments for smoking cessation, and smoking prevalence among health care professionals. See the table of contents and links to articles here.